Objective DNMT3B,de novo methyltransferase,is related to abnormal methylation of tumor suppressor genes and its overexpr......

目的 检测人胰腺癌组织中DNA甲基化转移酶3b( DNMT3b)的表达,分析其与肿瘤临床病理特征的相关性.方法 应用蛋白质印迹法检测12例配......

目的构建DNA甲基转移酶3B(DNMT3B)的一种异构体3B7的真核质粒表达载体,在体外评价其对人胚肾细胞株293A增殖影响。方法据GenBank中......

BACKGROUND:?Alterations in DNA methylation occur during the pathogenesis of human tumors. In this study, we investigated......